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Philipps-University of Marburg
Dept. of Gastroenterology
Baldingerstrasse
D-35043 Marburg

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Project leader

Prof. Dr. Thomas Gress

Prof. Dr. Thomas Gress

Secretariat:
Phone: +49 6421 586 6460
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Project staff

Priv.-Doz. Dr. Patrick Michl

Priv.-Doz. Dr. Patrick Michl

   
Dr.rer nat. Malte Buchholz

Priv.-Doz. Dr. Malte Buchholz

   
Esther Buchholz

Esther Buchholz

   
Dr.rer nat. Malte Buchholz

Albrecht Neesse, MD, PhD

Institute presentation

The medical faculty of the Philipps-University Marburg is one of the oldest medical faculties in Germany and has a strong record in translational medical research, with special focus on tumour biology and inflammation research. The faculty has recently established the interdisciplinary graduate college “Tumour and Inflammation”, funded by the state of Hessia within its LOEWE research initiative. The division of Gastroenterology, headed by Prof. Dr. T.M. Gress, has a long-standing expertise in high-throughput genomic analyses of gastrointestinal tumours, functional analysis of candidate genes and characterization of new therapeutic targets in pancreatic cancer, as well as characterization of the crosstalk between cancer cells and stromal components in pancreatic tumours. Among others, our group has established the first expression profile of a solid tumour as early as 1996 (Gress et al1996), has provided global gene expression analyses of stellate cell populations from different organs (Buchholz et al 2005) and characterized pro-invasive effects of tumour cell-stellate cell interaction in pancreatic cancer (Neesse et al 2007), as well as identified and characterized novel candidate genes with partly concurrent roles in tumour and immune cells (e.g. Ripka et al 2007, Buchholz et al 2006, Michl et al 2005, Weber et al 2001). In addition to our translational research tasks, we have a large clinical department which is a referral center for gastrointestinal tumours in central Germany. In this function, we are actively involved in large mono- and multicentric clinical trials for diagnosis, treatment and prevention of gastrointestinal tumours. Prof. Gress has ample experience in managing and coordinating multidisciplinary research projects. He has previously coordinated 4 EU-Projects, including the FP 6 integrated project “Novel molecular diagnostic tools for the prevention and diagnosis of pancreatic cancer” (MolDiag-Paca), and is currently coordinating the pancreatic cancer translational genome research network (PaCa-Net) within the German National Genome Research Network initiative (NGFNplus).

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